OBTAINING DRY EXTRACTS FROM LICORICE ROOTS (GLYCYRRHIZA GLABRA) AND ITS STANDARDIZATION

Licorice (Glycyrrhiza glabra) root has long been used in traditional medicine due to its various therapeutic properties. One of the main active components licorice is glycyrrhizin, which shown possess numerous pharmacological effects. Glycyrrhizin, one major compounds present root, anti-inflammatory, antioxidant, and anti-tumor propertiesas well as antiviral properties against influenza virus coronavirus COVID-19. The demand for extracts increasing, particularly use food pharmaceutical industries. However, quality consistency can vary depending on extraction method used. Therefore, aim this study was optimise technology obtaining dry from roots standardise process increased final product. In study, two different methods were compared: ultrasound-assisted using water alcohol-water solvents. extracted samples then subjected control tests, including glycyrrhizin content moisture content. obtained determined high-performance liquid chromatography (HPLC). standardisation extract performed according Pharmacopoeia Eurasian Economic Union. results showed that optimised with ultrasound, it yielded a higher compared ethanol ultrasoundand optimal conditions an time 60 minutes, frequency ultrasound bath at 40 kHz, temperature 30°C, solid-to-liquid ratio 1:6. confirmed presence glycyrrhizic acid purity extract.